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CAS No. 224452-66-8 | RETAPAMULIN

Name:RETAPAMULIN CAS No.224452-66-8 MF:C30H47NO4S MW:517.76 Purity:97% Package: 5g,25g,200g,500g,1kg Worldwide Delivery

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Biochemicals

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Product introduction

Introduction and application of CAS No. 224452-66-8 | RETAPAMULIN

Synonyms:RetapaMulin(SB-275833);

(3aS,4R,5S,6S,8R,9R,9aR,10R)-2-(exo-8-Methyl-8-azabicyclo[3.2.1]octan-3-ylsulfanyl)aceticacid5-hydroxy-4,6,9,10-tetraMethyl-1-oxo-6-vinylperhydro-3a,9-propanocyclopentacycloocten-8-ylester;

RetapaMulinAPI;

tetapaMulin;

(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetraMethyl-9-oxotricyclo[5.4.3.0^{1,8}]tetradecan-6-yl2-{[(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate;

Rebapamulin;SB-275833

Specification:

ITEMS	SPECIFICATION
CAS	224452-66-8
MF	C30H47NO4S
MW	517.76
Boiling point	594.9±50.0 °C
Density	1.16±0.1 g/cm3
Acidity coefficient	14.65±0.70
Solubility	Insoluble in water; ≥114.8 mg/mL in ethanol; ≥16.15 mg/mL, soluble in DMSO
Form	Solid
Storage condition	2-8°C

Introduction:

Retamorelin is a semisynthetic pleuromutilin derived from the reaction of pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine, which enables formulation as Stable hydrochloride salt. Retamorelin is a broad-spectrum antibiotic with no cross-resistance to existing antibiotic classes and is the first pleuromutilin approved for human use. Like all pleuromutilins, retamorelin inhibits protein synthesis by binding to domain V of 23S rRNA.

use:

Retamorelin is an effective antibacterial agent against Gram-positive bacteria, particularly Staphylococcus aureus and Streptococcus pyogenes.

Biological activity:

Retapamulin (SB-275833) is a topical antibiotic that binds to E. coli and S. aureus ribosomes with similar efficacy, with a Kd value of 3 nM.

Package and transportation :

Package: 10g,25g,50g,100g,250g